Patient Information
Learn about Evomela® (melphalan) for injection
What is Evomela®?
Evomela® is a prescription medicine also known as melphalan used in people with a type of cancer called multiple myeloma.1
Evomela® is used as a “conditioning treatment” (doctors sometimes call this myeloablation) for people who have multiple myeloma prior to a procedure called stem cell transplantation.1
Understanding the Language
Definition: Conditioning Treatment
The treatments (or regimen) used to prepare a patient for stem cell transplantation. Conditioning helps make room in the patient’s bone marrow for new blood stem cells to grow, helps prevent the patient’s body from rejecting the transplanted cells, and may help reduce cancer cells (in this case, multiple myeloma cells) that are in the body.2
Definition: Stem cell transplantation
A procedure in which a person receives blood stem cells, which make any type of blood cell.2
Evomela® is the only formulation of melphalan approved by the U.S. Food and Drug Administration for high-dose conditioning treatment.1 Please talk with your healthcare professionals to learn more about Evomela® and for more information about conditioning treatment before stem cell transplantation. Call your healthcare professional for medical advice about side effects. You are encouraged to report negative side effects to the FDA. Visit www.FDA.gov/medwatch or call 1-800-FDA-1088.
References
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Evomela® Prescribing Information. Acrotech Biopharma Inc.
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National Institutes of Health, National Cancer Center. Conditioned response [definition]. Accessed June 17, 2025. https://www.cancer.gov/publications/dictionaries/cancer-terms/def/conditioned-response.
